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Add Entrez Gene IDs to a Data Frame

add_entrez.Rd

Maps gene symbols from a specified column to Entrez IDs using clusterProfiler::bitr and joins them back to the original data frame. It also cleans gene symbols that may contain multiple entries separated by semicolons.

Usage

add_entrez(DE, org = org.Hs.eg.db::org.Hs.eg.db, gene_col = "Genes")

Arguments

DE

A data frame, such as one containing differential expression results.

org

An organism annotation database object (e.g., org.Hs.eg.db).

gene_col

A character string specifying the name of the column in DE that contains the gene symbols.

Value

A data frame with an appended ENTREZID column containing the mapped IDs. Returns NULL if no genes can be successfully mapped.