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Calculate Coefficient of Variation (CV) for Protein Groups

get_CVs.Rd

Calculates the coefficient of variation (CV) for each protein, grouped by an experimental condition. The CV is a standardized measure of dispersion, calculated as the standard deviation divided by the mean, and is often used to assess the reproducibility of replicates within a condition group.

Usage

get_CVs(object, condition, min_samples = 2)

# S4 method for class 'SummarizedExperiment'
get_CVs(object, condition, min_samples = 2)

Arguments

object

A SummarizedExperiment object.

condition

A character string specifying the column name in the colData slot which defines the replicate groups.

min_samples

The minimum number of replicates in a group required to calculate CVs. Groups with fewer samples will be skipped. Defaults to 2.

Value

A data frame in long format with columns for Protein, CV (in percent), and Condition.