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Perform Gene Ontology (GO) Gene Set Enrichment Analysis (GSEA)

gse_go.Rd

A wrapper around clusterProfiler::gseGO to perform GSEA for Gene Ontology terms on a ranked list of genes.

Usage

gse_go(
  gene_list,
  enrich_pvalue = 1,
  org = org.Hs.eg.db::org.Hs.eg.db,
  ont = "BP"
)

Arguments

gene_list

A named numeric vector of genes. Names should be Entrez IDs and values should be the ranking metric (e.g., log2 fold change).

enrich_pvalue

The p-value cutoff for enrichment. Defaults to 1 (no cutoff).

org

An organism annotation database (e.g., org.Hs.eg.db).

ont

GO ontology to test. One of "BP", "MF", "CC", or "ALL".

Value

A gseResult object if the analysis is successful and finds enriched terms, otherwise NULL.